Full Length Research Article 

RETRACTED ARTICLE: In-vitro study on antioxidant status of Zinc NPs and crude extract of Ayurvedic herbal formulation

Jaafar Faez Kadhim Alsadooni^1*, Sura Razzaq Khudhair²

Adv. life sci., vol. 11, no. 2, pp. 338-345, May 2024
*^- Corresponding Author: Jaafar Faez Kadhim (jaafaralsadoon@gmail.com)
Authors' Affiliations

Abstract
Introduction
Methods
Results
Discussion
References 

Abstract

Background: To create and evaluate cutting-edge therapeutic composition on biosynthesized nanoparticles exhibiting varied biological activity, nanotechnology is a novel and forward-thinking method. Increased antioxidant activity decreased toxicity to free radicals as well as cancer cells, and other benefits are achieved carefully by regulating the form and nanoparticle dimensions.

Methods: Nanostructures biosynthesized utilizing Liv-Pro-08 AHF showed a strong antioxidant effect. The creation of novel and more efficient antioxidants may benefit from the usage of nanoparticles. It is noteworthy that the resulting nanoparticles exhibit more biological processes than the extract. This research aims to calculate if there are any noticeable differences in the behaviour of leaf extracts and the many nanomaterials obtained from the aqueous-based separation of Liv-Pro-08 Ayurveda herbal-based formulations.

Results: Several in-vitro free radical scavenging experiments were used to determine whether or not Liv-pro-08 nanoparticles possessed any antioxidant properties. Zinc nanoparticles generated from Liv-pro-08 ayurvedic formulation demonstrated dose-dependent suppression of DPPH, as well as concentration-dependent lowering power potential, indicating that the nanomaterials contain free radical scavenging capability to produce the antioxidant effect.

Conclusion: Nanoparticles might be useful for the development of newer and more potent antioxidants. It is worth mentioning that the resultant nanoparticles possess an elevated biological activity in comparison to the extract. The data represented in our study contribute to a novel and unexplored area of nano materials as alternative medicine.

Keywords: Antioxidants; Biosynthesis; Leaf extract; Liv-pro-08; Zinc   

Retraction Note

03 Dec 2025: The Editor-in-Chief has approved retraction of this article on the following grounds.

1. The paper's "Methods" section is in direct contradiction with its "Results" section regarding the plant material used.
Methods: The "Selection of Plant Species" section explicitly states the experiment used the "Fruits of Ficus glomerata and seeds of Nigella sativa, Entada pursaetha".
Results: The "Results" section (and the legend for Figure 1) presents data (XRD, TEM, etc.) exclusively from a completely different, unmentioned plant: "G. moluccana".

2. The text in the "Results" section is scientifically unsound.

• The text states, "the activity of catalase in Glutathione peroxidase is highest". This is biologically impossible. Catalase and Glutathione peroxidase are two different enzymes; one cannot be in the other.
• The text reports data with missing symbols (e.g., "22.710.90 units/mg protein" instead of 22.71 ± 0.90) and nonsensical units (e.g., "inhibition concentration of ZnNPs was found to be 0.18% µg/ml").

The authors do not agree to this retraction.